Media Center
epiXchange conference
23 May 2018, Brussels
The epiXchange conference 2018 was fully recorded. Here you can find the full live-stream as well as special cutouts: the opening & key-note speech, the project overviews, the five thematic sessions and the concluding remarks of epiXchange 2018. You can find the single talks of the speakers in the drop-down menu next to the relevant session. To discover the image gallery of epiXchange 2018 please follow the link below:
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Conference Feature
epiXchange2018
180 Seconds Interviews
with epiXchange2018 Organisers
- Helen Cross
EpiCARE - Renzo Guerrini
DESIRE - David Henshall
EpimiRNA - Sergiusz Jóźwiak
EPISTOP - Merab Kokaia
EPITARGET - Janet Mifsud | Asla Pitkänen
DESIRE | EPITARGET - Michele Simonato
Epixchange
Opening Speech
David Henshall, EpimiRNA
- Video
Project Overviews
Coordinators of Projects
- DESIRE
Renzo Guerrini - EpimiRNA
David Henshall - EPIPGX
Gianpiero Cavalleri - EPISTOP
Sergiusz Jóźwiak - EPITARGET
Merab Kokaia - Epixchange
Michele Simonato - EpiCARE
Helen Cross
Key Note Speech
Karim Berkouk, DG Research & Innovation at European Commission
- Video Presentation
Translational Research in Biomarkers
Chairs: A. Pitkänen (University of Eastern Finland), M. Simonato (Università degli Studi di Ferrara)
- Short overview
A.Pitkänen (EPITARGET – University of Eastern Finland)
- Epigenetic biomarkers in FCDs
K. Kobow (DESIRE – Friedrich-Alexander-Universität Erlangen-Nürnberg) - MicroRNA as biomarkers of epilepsy and status epilepticus
F. Rosenow (EpimiRNA – Goethe-Universität Frankfurt & Philipps-Universität Marburg) - Predictors of adverse reactions to AEDs
G. Cavalleri (EpiPGX – Royal College of Surgeons in Ireland)
- EEG changes as biomarker for emerging epilepsy in TSC
L. Lagae (EPISTOP – Katholieke Universiteit Leuven) - HMGB1 as a predictive biomarker for preclinical and clinical studies
A. Vezzani (EPITARGET – Mario Negri Institute) - Questions & Answers
All Speakers
Due to confidentiality issues not publicly available.
Genetics of Epilepsy - Therapeutics Implications
Chairs: D. J. Kwiatkowski (Harvard University), R. Guerrini (Università degli Studi di Firenze)
- Short overview
R. Guerrini (DESIRE – Università degli Studi di Firenze) - Genetics of epileptogenic disorders: update and consequences on patients' therapeutic management
R. Guerrini (DESIRE – Università degli Studi di Firenze) - The emerging role of genetics in the clinical care pathway
R. Nabbout (EpiCARE - CHU Paris) - Genetic variation in microRNAs and their targets in epilepsy
I. Lopes-Cendes (EpimiRNA – Universidade Estadual de Campinas) - Predictors of responses to AEDs
H. Lerche (EpiPGX – Universität Tübingen) - Genetics and mosaicism in Tuberous Sclerosis Complex: preliminary analysis of association with seizure phenotype in EPISTOP
D. Kwiatkowski (EPISTOP – Harvard University) - Functional epigenomic dissection of epilepsy in human brain biopsy tissue and corresponding mouse models
A. Becker (EPITARGET – Universität Bonn)
- Questions & Answers
All Speakers
Due to confidentiality issues not publicly available.
Innovation Therapeutics & Translation
Chairs: F. Rosenow (Goethe-Universität Frankfurt & Philipps-Universität Marburg), M. Kokaia (Lunds Universitet)
- Short overview
M. Kokaia (EPITARGET - Lunds Universitet) - Innovative therapeutic strategies for epileptic encephalopathies
F. Benfenati (DESIRE – Istituto Italiano Di Tecnologia) - Improving clinical trials in epilepsy: addressing the hurdles and filling the gaps
E. Perucca (EpiCARE – ILAE/ Università degli Studi di Pavia) - MicroRNAs as targets for seizure control and disease-modification
D. Henshall (EpimiRNA – Royal College of Surgeons in Ireland) - Preseizure vs postseizure treatment of epilepsy - pros and cons
S. Jóźwiak (EPISTOP – Warszawski Uniwersytet Medyczny) - Evaluation of tolerability and antiepileptogenic efficacy of multitargeted drug combinations by a two-stage approach
W. Löscher (EPITARGET – Stiftung Tierarztliche Hochschule Hannover) - Differential effect of neuropeptides on excitatory synaptic transmission in human epileptic hippocampus
M. Ledri (Epixchange – Lunds Universitet)
- Questions & Answers
All Speakers
Understanding Co-Morbidities in the Epilepsies
Chairs: H. Cross (University College London), S. Jóźwiak (Warszawski Uniwersytet Medyczny)
- Short overview
S. Jóźwiak (EPISTOP – Warszawski Uniwersytet Medyczny) - Perspectives for investigating physiopathological mechanisms of co-morbidities in epilepsy
A. Represa (DESIRE – INSERM) - Predictors of response and resistance and co-morbidities
C. Leu (EpiPGX – University College London) - Autism in tuberous sclerosis: early developmental trajectories, potential biomarkers and treatment strategies
P. Curatolo (EPISTOP – Policlinico Tor Vergata) - Systems genetic evidence for a convergence of epilepsy and its co-morbidies on shared molecular pathways
M. Johnson (EPITARGET – Imperial College London) - Effects on seizures and epilepsy co-morbidities of encapsulated BDNF-producing cells
C. Falcicchia (Epixchange – Università degli Studi di Ferrara)
- Questions & Answers
All Speakers
Biobanks and Databases - Basis for Translational Research
Chairs: S. Sisodiya (University College London), K. Kobow (Friedrich-Alexander-Universität Erlangen-Nürnberg)
- Short overview
K. Kobow (DESIRE – Friedrich-Alexander-Universität Erlangen-Nürnberg) - Success of the European Epilepsy Brain Bank
I. Blümcke (DESIRE & EpiCARE – ILAE/ Friedrich-Alexander-Universität Erlangen-Nürnberg) - Multi-omic atlas of functional microRNA for epilepsy
A. Ahonen-Bishopp(EpimiRNA – BCPlatforms) - Controlled access resources for genetic and pharmacogenetics research for epilepsy
R. Krause (EpiPGX – Université du Luxembourg) - Biobanking in Tuberous Sclerosis Complex : challenges and opportunities for understanding epilepsy and cognitive and behavioural co-morbidities
E. Aronica (EPISTOP – Universiteit van Amsterdam) - Database for powered preclinical multicenter trial
A.Pitkänen (EPITARGET – University of Eastern Finland) - Questions & Answers
All Speakers
Concluding Remarks
Janet Mifsud, DESIRE – University of Malta
- Video Presentation